Novel Drug Delivery System book, notes pdf - b pharmacy 4th year (7th semester) - JNTUH
Novel Drug Delivery System
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B Pharmacy 4th year (1st sem) | 7th Semester | JNTUH
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Unit - 1
Controlled drug delivery systems
Introduction, terminology/definitions and rationale, advantages, disadvantages, selection of drug candidates. Approaches to design-controlled release formulations based on diffusion, dissolution and ion exchange principles. Physicochemical and biological properties of drugs relevant to controlled release formulations
Polymers
Introduction, classification, properties, advantages and application of polymers in formulation of controlled release drug delivery systems.
Unit - 2
Microencapsulation
Definition, advantages and disadvantages, microspheres /microcapsules, microparticles, methods of microencapsulation, applications
Mucosal Drug Delivery system
Introduction, Principles of bioadhesion / mucoadhesion, concepts, advantages and disadvantages, transmucosal permeability and formulation considerations of buccal delivery systems
Implantable Drug Delivery Systems
Introduction, advantages and disadvantages, concept of implantsand osmotic pump.
Unit - 3
Transdermal Drug Delivery Systems
Introduction, Permeation through skin, factors affecting permeation, permeation enhancers, basic components of TDDS, formulation approaches
Gastroretentive drug delivery systems
Introduction, advantages, disadvantages, approaches for GRDDS – Floating, high density systems, inflatable and gastroadhesive systems and their applications
Nasopulmonary drug delivery system
Introduction to Nasal and Pulmonary routes of drug delivery, Formulation of Inhalers (dry powder and metered dose), nasal sprays, nebulizers.
Unit - 4
Nanotechnology and its Concepts
Concepts and approaches for targeted drug delivery systems, advantages and disadvantages, introduction to liposomes, niosomes, nanoparticles, monoclonal antibodies and their applications.
Unit - 5
Ocular Drug Delivery Systems
Introduction, intra ocular barriers and methods to overcome – Preliminary study, ocular formulations and ocuserts
Intrauterine Drug Delivery Systems
Introduction, advantages and disadvantages, development of intra uterine devices (IUDs) and applications
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